› 7jvs

X-ray diffraction
2.3Å resolution

Crystal Structure of an Essential Ribosomal Processing Protease Prp from S. aureus in complex with a Substrate Peptide

Released:
DOI: 10.2210/pdb7jvs/pdb
PDB entry 7jvs coloured by chain, front view.
PDB entry 7jvs coloured by chain, side view.
PDB entry 7jvs coloured by chain, top view.
Source organism: Staphylococcus aureus
Entry authors: Wright HT, Peterson D

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173459 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribosomal processing cysteine protease Prp Chains: B, D
Molecule details ›
Chains: B, D
Length: 106 amino acids
Theoretical weight: 11.7 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q2FXS9 (Residues: 1-106; Coverage: 100%)
Gene names: SAOUHSC_01756, prp
Sequence domains: Cysteine protease Prp
Large ribosomal subunit protein bL27 Chain: C
Molecule details ›
Chain: C
Length: 14 amino acids
Theoretical weight: 1.41 KDa
Source organism: Staphylococcus aureus
Expression system: Not provided
UniProt:
  • Canonical: Q2FXT0 (Residues: 3-14; Coverage: 13%)
Gene names: SAOUHSC_01755, rpmA

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand NI 1 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2221
Unit cell:
a: 52.552Å b: 56.824Å c: 130.278Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.224 0.264
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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