› 7jzo

X-ray diffraction
1.61Å resolution

CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALTPP

Released:
DOI: 10.2210/pdb7jzo/pdb
PDB entry 7jzo coloured by chain, front view.
PDB entry 7jzo coloured by chain, side view.
PDB entry 7jzo coloured by chain, top view.
Source organisms:
Entry authors: Gill NP, Madden DR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168321 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Golgi-associated PDZ and coiled-coil motif-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 87 amino acids
Theoretical weight: 9.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HD26 (Residues: 284-370; Coverage: 19%)
Gene names: CAL, FIG, GOPC
Sequence domains: PDZ domain
LyCALTPP peptide core Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 amino acids
Theoretical weight: 1.09 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand GOL 2 x GOL
Ligand QTU 2 x QTU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 36.804Å b: 47.812Å c: 97.926Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.175 0.206
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links