› 7jzq

X-ray diffraction
1.35Å resolution

CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALPMB

Released:
DOI: 10.2210/pdb7jzq/pdb
PDB entry 7jzq coloured by chain, front view.
PDB entry 7jzq coloured by chain, side view.
PDB entry 7jzq coloured by chain, top view.
Source organisms:
Entry authors: Gill NP, Madden DR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168323 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Golgi-associated PDZ and coiled-coil motif-containing protein Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HD26 (Residues: 284-370; Coverage: 19%)
Gene names: CAL, FIG, GOPC
Sequence domains: PDZ domain
LyCALPMB peptide core Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.09 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand VU1 1 x VU1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 33.097Å b: 49.659Å c: 49.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.173 0.186
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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