› › Function and Biology

Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor cis-22a

Source organism: Homo sapiens
Biochemical function: calcium channel activity
Biological process: transmembrane transport
Cellular component: membrane

Quick links

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00520
Domain description: Ion transport protein
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
The deposited structure of PDB entry 7k4b contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Transient receptor potential cation channel subfamily V member 6. Showing 1 copy in chain A.

PF00023
Domain description: Ankyrin repeat
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
The deposited structure of PDB entry 7k4b contains 4 copies of Pfam domain PF00023 (Ankyrin repeat) in Transient receptor potential cation channel subfamily V member 6. Showing 1 copy in chain A.

PF12796
Domain description: Ankyrin repeats (3 copies)
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
The deposited structure of PDB entry 7k4b contains 4 copies of Pfam domain PF12796 (Ankyrin repeats (3 copies)) in Transient receptor potential cation channel subfamily V member 6. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002110
Domain description: Ankyrin repeat
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
IPR008344
Domain description: Transient receptor potential cation channel subfamily V member 5/6
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
IPR036770
Domain description: Ankyrin repeat-containing domain superfamily
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
IPR008345
Domain description: Transient receptor potential cation channel subfamily V member 6
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
IPR005821
Domain description: Ion transport domain
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6
IPR024862
Domain description: Transient receptor potential cation channel subfamily V
Occurring in:
  1. Transient receptor potential cation channel subfamily V member 6

Quick links