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A 3.4 Angstrom cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

Source organism: Human coronavirus NL63
Biochemical function: not assigned
Biological process: endocytosis involved in viral entry into host cell
Cellular component: virion membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF19214
Domain description: Coronavirus spike glycoprotein S2, intravirion
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7kip contains 3 copies of Pfam domain PF19214 (Coronavirus spike glycoprotein S2, intravirion) in Spike glycoprotein. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF01601
Domain description: Coronavirus spike glycoprotein S2
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7kip contains 3 copies of Pfam domain PF01601 ( Coronavirus spike glycoprotein S2) in Spike glycoprotein. Showing 1 copy in chain A.

PF19209
Domain description: Coronavirus spike glycoprotein S1, C-terminal
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7kip contains 3 copies of Pfam domain PF19209 ( Coronavirus spike glycoprotein S1, C-terminal) in Spike glycoprotein. Showing 1 copy in chain A.

PF01600
Domain description: Coronavirus spike glycoprotein S1
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7kip contains 3 copies of Pfam domain PF01600 (Coronavirus spike glycoprotein S1) in Spike glycoprotein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR043473
Domain description: Spike glycoprotein S2 superfamily, coronavirus
Occurring in:
  1. Spike glycoprotein
IPR043614
Domain description: Spike glycoprotein S2, coronavirus, C-terminal
Occurring in:
  1. Spike glycoprotein
IPR044874
Domain description: Spike glycoprotein S2, coronavirus, heptad repeat 2
Occurring in:
  1. Spike glycoprotein
IPR044873
Domain description: Spike glycoprotein S2, coronavirus, heptad repeat 1
Occurring in:
  1. Spike glycoprotein
IPR002552
Domain description: Spike glycoprotein S2, coronavirus
Occurring in:
  1. Spike glycoprotein
IPR043607
Domain description: Coronavirus spike glycoprotein S1, C-terminal
Occurring in:
  1. Spike glycoprotein
IPR002551
Domain description: Spike glycoprotein S1, coronavirus
Occurring in:
  1. Spike glycoprotein
IPR042552
Domain description: Spike glycoprotein, Alphacoronavirus
Occurring in:
  1. Spike glycoprotein

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