Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Claudin-4 and Heat-labile enterotoxin B chain (preferred)
PDBe Complex ID:
PDB-CPX-126980 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Claudin-4
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 22.61 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: PMP-22/EMP/MP20/Claudin family
Length: 214 amino acids
Theoretical weight: 22.61 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
O14493 (Residues: 1-209; Coverage: 100%)
Sequence domains: PMP-22/EMP/MP20/Claudin family
Heat-labile enterotoxin B chain
Molecule details ›
Chain: B
Length: 134 amino acids
Theoretical weight: 15.11 KDa
Source organism: Clostridium perfringens
Expression system: Trichoplusia ni
UniProt:
Length: 134 amino acids
Theoretical weight: 15.11 KDa
Source organism: Clostridium perfringens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P01558 (Residues: 192-319; Coverage: 40%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.3.1
Spacegroup:
P212121
Expression system: Trichoplusia ni
