PDB 7kth structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

Biochemical function:

DNA polymerase activity

Biological process:

DNA repair

Cellular component:

nucleus

Sequence domains:

4 more domains

Structure analysis Details

Assembly composition:

hetero tetramer (preferred)

Assembly name:

DNA-directed DNA/RNA polymerase mu and DNA (preferred)

PDBe Complex ID:

PDB-CPX-121498 (preferred)

Entry contents:

1 distinct polypeptide molecule
3 distinct DNA molecules

Macromolecules (4 distinct):

DNA-directed DNA/RNA polymerase mu Chain: A

Molecule details ›

Chain: A
Length: 356 amino acids
Theoretical weight: 40.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

Canonical: Q9NP87 (Residues: 132-494; Coverage: 71%)

Gene names: POLM, polmu
Sequence domains:

DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3') Chain: T

Molecule details ›

Chain: T
Length: 9 nucleotides
Theoretical weight: 2.72 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(*CP*GP*TP*AP*(8OG))-3') Chain: P

Molecule details ›

Chain: P
Length: 5 nucleotides
Theoretical weight: 1.54 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(P*GP*CP*CP*G)-3') Chain: D

Molecule details ›

Chain: D
Length: 4 nucleotides
Theoretical weight: 1.19 KDa
Source organism: synthetic construct
Expression system: Not provided