• <div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7l5e</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7l5e</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7l5e</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7l5e</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7l5e</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7l5e</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>Exportin-1</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>MAGNESIUM ION</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>GLYCEROL</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> contains 1 copy of <span class='highlight'>selinexor, bound form</span>. Front view.</div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
  • <div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>7l5e</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTP-binding nuclear protein Ran</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Ran-specific GTPase-activating protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Exportin-1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>selinexor, bound form</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>
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7l5e Overview