7l7e

X-ray diffraction
3Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-209813 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
heavy chain of human monoclonal antibody AZD8895 Chains: A, H, I, T
Molecule details ›
Chains: A, H, I, T
Length: 225 amino acids
Theoretical weight: 23.94 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
light chain of human monoclonal antibody Fab AZD8895 Chains: B, J, L, U
Molecule details ›
Chains: B, J, L, U
Length: 216 amino acids
Theoretical weight: 23.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
heavy chain of human monoclonal antibody Fab AZD1061 Chains: C, E, M, O
Molecule details ›
Chains: C, E, M, O
Length: 236 amino acids
Theoretical weight: 25.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
light chain of human monoclonal antibody Fab AZD1061 Chains: D, F, N, P
Molecule details ›
Chains: D, F, N, P
Length: 219 amino acids
Theoretical weight: 24.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chains: G, K, S, b
Molecule details ›
Chains: G, K, S, b
Length: 215 amino acids
Theoretical weight: 24.23 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 330-529; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P21
Unit cell:
a: 97.152Å b: 152.525Å c: 199.244Å
α: 90° β: 94.74° γ: 90°
R-values:
R R work R free
0.218 0.215 0.273
Expression system: Homo sapiens