› 7l8f

Electron Microscopy
3.66Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168409 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Envelope glycoprotein gp160 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 664 amino acids
Theoretical weight: 74.67 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-661; Coverage: 74%)
Gene name: env
Sequence domains:
Rh.33172 pAbC-2 Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 127 amino acids
Theoretical weight: 10.83 KDa
Source organism: Macaca mulatta
Rh.33172 pAbC-2 Light Chain Chain: L
Molecule details ›
Chain: L
Length: 107 amino acids
Theoretical weight: 9.12 KDa
Source organism: Macaca mulatta

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Ligand NAG 6 x NAG
Ligand BMA 3 x BMA
Ligand MAN 6 x MAN
Carbohydrate polymer : NEW Components: NAG
Ligand NAG 22 x NAG
1 bound ligand:
Ligand NAG 49 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.66Å
Relevant EMDB volumes: EMD-23232
Expression system: Homo sapiens

Quick links

Citations

2 review citations

Bringing immunofocusing into focus.
Musunuri et al. (2024)
1 more

1 mention without citation

From structure to sequence: Antibody discovery using cryoEM.
Antanasijevic et al. (2022)