› 7lhm

X-ray diffraction
1.5Å resolution

Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal

Released:
DOI: 10.2210/pdb7lhm/pdb
PDB entry 7lhm coloured by chain, front view.
PDB entry 7lhm coloured by chain, side view.
PDB entry 7lhm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ehyaei N, Geiger JH, Borhan B

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156128 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 15.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P50120 (Residues: 2-134; Coverage: 99%)
Gene names: CRBP2, RBP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

3 bound ligands:
Ligand ACT 2 x ACT
Ligand RET 2 x RET
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P1
Unit cell:
a: 30.979Å b: 36.479Å c: 63.896Å
α: 90.81° β: 93.4° γ: 115.9°
R-values:
R R work R free
0.199 0.198 0.222
Expression system: Escherichia coli

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