› 7lkj

X-ray diffraction
2.79Å resolution

Crystal structure of Helicobacter pylori aminofutalosine deaminase (AFLDA)

Released:
DOI: 10.2210/pdb7lkj/pdb
PDB entry 7lkj coloured by chain, front view.
PDB entry 7lkj coloured by chain, side view.
PDB entry 7lkj coloured by chain, top view.
Source organism: Helicobacter pylori
Primary publication:
Aminofutalosine Deaminase in the Menaquinone Pathway of Helicobacter pylori.
Feng M, Harijan RK, Harris LD, Tyler PC, Fröhlich RFG, Brown M, Schramm VL
Biochemistry 60 1933-1946 (2021)
PMID: 34077175

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195678 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amidohydrolase-related domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 423 amino acids
Theoretical weight: 47.52 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ZMG8 (Residues: 1-409; Coverage: 100%)
Gene names: jhp_0252, orf1
Sequence domains: Amidohydrolase family

Ligands and Environments

2 bound ligands:
Ligand FE 3 x FE
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 73.295Å b: 73.295Å c: 157.495Å
α: 90° β: 98.59° γ: 90°
R-values:
R R work R free
0.254 0.252 0.287
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues.
Feng et al. (2023)

1 mention without citation

Aminofutalosine Deaminase in the Menaquinone Pathway of Helicobacter pylori.
Feng et al. (2021)