Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-102776 (preferred)
Entry contents:
6 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct RNA molecule
1 distinct DNA molecule
1 distinct RNA molecule
Macromolecules (8 distinct):
La-related protein 7 homolog
Molecule details ›
Chain: H
Length: 542 amino acids
Theoretical weight: 64.21 KDa
Source organism: Tetrahymena thermophila
UniProt:
Sequence domains:
Length: 542 amino acids
Theoretical weight: 64.21 KDa
Source organism: Tetrahymena thermophila
UniProt:
- Canonical:
W7X6T2 (Residues: 1-542; Coverage: 100%)
Sequence domains:
Telomerase reverse transcriptase
Molecule details ›
Chain: A
Length: 1117 amino acids
Theoretical weight: 133.49 KDa
Source organism: Tetrahymena thermophila
UniProt:
Sequence domains:
Length: 1117 amino acids
Theoretical weight: 133.49 KDa
Source organism: Tetrahymena thermophila
UniProt:
- Canonical: O77448 (Residues: 1-1117; Coverage: 100%)
Sequence domains:
Telomeric repeat-binding subunit 1
Replication protein A 32 kDa subunit
Replication protein A 14 kDa subunit
Telomerase-associated protein of 50 kDa
