7lpn

Electron Microscopy
3.61Å resolution

Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-212180 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (7 distinct):
Transmembrane protein gp41 Chains: A, B, E
Molecule details ›
Chains: A, B, E
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
Envelope glycoprotein gp160 Chains: C, F, G
Molecule details ›
Chains: C, F, G
Length: 476 amino acids
Theoretical weight: 53.3 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-505; Coverage: 55%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
J3 VHH Chains: D, H, I
Molecule details ›
Chains: D, H, I
Length: 130 amino acids
Theoretical weight: 14.49 KDa
Source organism: Lama glama
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.61Å
Relevant EMDB volumes: EMD-23480
Expression system: Homo sapiens