› 7luc

Electron Microscopy
3.21Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-207709 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Fusion glycoprotein F0 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 527 amino acids
Theoretical weight: 58.62 KDa
Source organism: Respiratory syncytial virus
Expression system: Homo sapiens
UniProt:
  • Canonical: C3UPB8 (Residues: 26-513; Coverage: 85%)
Sequence domains: Fusion glycoprotein F0
01.4B Fab Heavy chain Chains: D, F, H
Molecule details ›
Chains: D, F, H
Length: 121 amino acids
Theoretical weight: 13.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
01.4B Fab Light chain Chains: E, G, I
Molecule details ›
Chains: E, G, I
Length: 112 amino acids
Theoretical weight: 12.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
32.4K Fab Heavy chain Chains: J, L, N
Molecule details ›
Chains: J, L, N
Length: 129 amino acids
Theoretical weight: 14.14 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
32.4K Fab Light chain Chains: K, M, O
Molecule details ›
Chains: K, M, O
Length: 107 amino acids
Theoretical weight: 11.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.21Å
Relevant EMDB volumes: EMD-23520
Expression system: Homo sapiens

Quick links

Citations

4 review citations

Engineering Self-Assembling Protein Nanoparticles for Therapeutic Delivery.
Olshefsky et al. (2022)
3 more

2 mentions without citation

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Mukhamedova et al. (2021)
1 more