› 7lva

Hybrid

Solution structure of the HIV-1 PBS-segment

Released:
DOI: 10.2210/pdb7lva/pdb
PDB entry 7lva coloured by chain, ensemble of 10 models, front view.
PDB entry 7lva coloured by chain, ensemble of 10 models, side view.
PDB entry 7lva coloured by chain, ensemble of 10 models, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity.
Song Z, Gremminger T, Singh G, Cheng Y, Li J, Qiu L, Ji J, Lange MJ, Zuo X, Chen SJ, Zou X, Boris-Lawrie K, Heng X
OpenAccess logo Nucleic Acids Res 49 5925-5942 (2021)
PMID: 33978756

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195879 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (103-MER) Chain: A
Molecule details ›
Chain: A
Length: 103 nucleotides
Theoretical weight: 33.25 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
Sequence domains: HIV primer binding site (PBS)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Experimental Method: X-ray solution scattering, Solution NMR
Expression system: Not provided

Quick links

Citations

2 review citations

Anomalous HIV-1 RNA, How Cap-Methylation Segregates Viral Transcripts by Form and Function.
Boris-Lawrie et al. (2022)
1 more

2 mentions without citation

Structural and computational studies of HIV-1 RNA.
Levintov et al. (2024)
1 more