› 7lzj

Electron Microscopy
2.7Å resolution

DpK2 bacteriophage tail spike depolymerase

Released:
DOI: 10.2210/pdb7lzj/pdb
PDB entry 7lzj coloured by chain, front view.
PDB entry 7lzj coloured by chain, side view.
PDB entry 7lzj coloured by chain, top view.
Source organism: Klebsiella phage GH-K3
Primary publication:
Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage.
Dunstan RA, Bamert RS, Belousoff MJ, Short FL, Barlow CK, Pickard DJ, Wilksch JJ, Schittenhelm RB, Strugnell RA, Dougan G, Lithgow T
OpenAccess logo Microbiol Spectr 9 e0102321 (2021)
PMID: 34431721
Related structures: EMD-23608

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244951 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Depolymerase; Depolymerase, capsule K2-specific Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 907 amino acids
Theoretical weight: 98.44 KDa
Source organism: Klebsiella phage GH-K3
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A3S7W7I3 (Residues: 1-907; Coverage: 100%)
  • Canonical: P0DTN8 (Residues: 1-907; Coverage: 100%)
Gene names: GHK3_32, RAD2_02

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-23608
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Biofilm Lifestyle in Recurrent Urinary Tract Infections.
Lila et al. (2023)
4 more

1 mention without citation

Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage.
Dunstan et al. (2021)