PDB 7m0d structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

Biochemical function:

DNA polymerase activity

Biological process:

DNA repair

Cellular component:

not assigned

Sequence domains:

3 more domains

Structure analysis Details

Assembly composition:

hetero pentamer (preferred)

Assembly name:

DNA polymerase lambda and DNA (preferred)

PDBe Complex ID:

PDB-CPX-121572 (preferred)

Entry contents:

1 distinct polypeptide molecule
4 distinct DNA molecules

Macromolecules (5 distinct):

DNA polymerase lambda Chains: A, B

Molecule details ›

Chains: A, B
Length: 346 amino acids
Theoretical weight: 38.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: Q9UGP5 (Residues: 234-575; Coverage: 60%)

Gene name: POLL
Sequence domains:

DNA (5'-D(*CP*GP*GP*CP*AP*GP*C)-3') Chains: G, K

Molecule details ›

Chains: G, K
Length: 7 nucleotides
Theoretical weight: 2.12 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(*CP*AP*GP*TP*GP*C)-3') Chains: F, J

Molecule details ›

Chains: F, J
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(P*GP*CP*CP*G)-3') Chains: H, L

Molecule details ›

Chains: H, L
Length: 4 nucleotides
Theoretical weight: 1.19 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(*AP*CP*TP*G)-3') Chains: E, I

Molecule details ›

Chains: E, I
Length: 4 nucleotides
Theoretical weight: 1.19 KDa
Source organism: synthetic construct
Expression system: Not provided