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7m0x Overview
![<div class='caption-body'>Hetero dimeric assembly 1 of PDB entry <span class='highlight'>7m0x</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Hetero dimeric assembly 1 of PDB entry 7m0x coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Hetero dimeric assembly 1 of PDB entry <span class='highlight'>7m0x</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Hetero dimeric assembly 1 of PDB entry 7m0x coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Hetero dimeric assembly 1 of PDB entry <span class='highlight'>7m0x</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Hetero dimeric assembly 1 of PDB entry 7m0x coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Hetero dimeric assembly 1 of PDB entry <span class='highlight'>7m0x</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_assembly_1_chain_front_image-800x800.png "Hetero dimeric assembly 1 of PDB entry 7m0x coloured by chain, front view.")
![<div class='caption-body'>Hetero dimeric assembly 1 of PDB entry <span class='highlight'>7m0x</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_assembly_1_chain_side_image-800x800.png "Hetero dimeric assembly 1 of PDB entry 7m0x coloured by chain, side view.")
![<div class='caption-body'>Hetero dimeric assembly 1 of PDB entry <span class='highlight'>7m0x</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_assembly_1_chain_top_image-800x800.png "Hetero dimeric assembly 1 of PDB entry 7m0x coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7m0x</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_deposited_chain_front_image-800x800.png "PDB entry 7m0x coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7m0x</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_deposited_chain_side_image-800x800.png "PDB entry 7m0x coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7m0x</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_deposited_chain_top_image-800x800.png "PDB entry 7m0x coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7m0x</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 7m0x coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7m0x</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 7m0x coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7m0x</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Serine/threonine-protein kinase B-raf</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Dual specificity mitogen-activated protein kinase kinase 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7m0x_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 7m0x coloured by chemically distinct molecules, top view.")