› 7mbl

X-ray diffraction
2.7Å resolution

Crystal structure of Equine Serum Albumin in complex with Cobalt (II)

Released:
DOI: 10.2210/pdb7mbl/pdb
PDB entry 7mbl coloured by chain, front view.
PDB entry 7mbl coloured by chain, side view.
PDB entry 7mbl coloured by chain, top view.
Source organism: Equus caballus
Primary publication:
Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids.
Wu D, Gucwa M, Czub MP, Cooper DR, Shabalin IG, Fritzen R, Arya S, Schwarz-Linek U, Blindauer CA, Minor W, Stewart AJ
OpenAccess logo Chem Sci 14 6244-6258 (2023)
PMID: 37325156

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chain: A
Molecule details ›
Chain: A
Length: 583 amino acids
Theoretical weight: 65.77 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: P35747 (Residues: 25-607; Coverage: 99%)
Gene name: ALB
Sequence domains: Serum albumin family

Ligands and Environments

2 bound ligands:
Ligand CO 5 x CO
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P61
Unit cell:
a: 93.312Å b: 93.312Å c: 141.51Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.213 0.289

Quick links

Citations

2 review citations

The current role and evolution of X-ray crystallography in drug discovery and development.
Bijak et al. (2023)
1 more