Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-160796 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
WD repeat-containing protein 41
Molecule details ›
Chain: A
Length: 459 amino acids
Theoretical weight: 51.78 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 459 amino acids
Theoretical weight: 51.78 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9HAD4 (Residues: 1-459; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Guanine nucleotide exchange protein SMCR8
Molecule details ›
Chain: B
Length: 937 amino acids
Theoretical weight: 105.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Vesicle coat protein involved in Golgi to plasma membrane transport
Length: 937 amino acids
Theoretical weight: 105.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q8TEV9 (Residues: 1-937; Coverage: 100%)
Sequence domains: Vesicle coat protein involved in Golgi to plasma membrane transport
Guanine nucleotide exchange factor C9orf72
Molecule details ›
Chain: C
Length: 481 amino acids
Theoretical weight: 54.39 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: C9orf72-like protein family
Length: 481 amino acids
Theoretical weight: 54.39 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q96LT7 (Residues: 1-481; Coverage: 100%)
Sequence domains: C9orf72-like protein family
ADP-ribosylation factor 1
Molecule details ›
Chain: E
Length: 166 amino acids
Theoretical weight: 18.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: ADP-ribosylation factor family
Length: 166 amino acids
Theoretical weight: 18.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P84077 (Residues: 17-180; Coverage: 91%)
Sequence domains: ADP-ribosylation factor family
