› 7mnk

X-ray diffraction
1.1Å resolution

Crystal structure of the tetramerization element of NUP358/RanBP2 (residues 805-832)

Released:
DOI: 10.2210/pdb7mnk/pdb
PDB entry 7mnk coloured by chain, front view.
PDB entry 7mnk coloured by chain, side view.
PDB entry 7mnk coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bley CJ, Nie S, Mobbs GW, Petrovic S, Gres AT, Liu X, Mukherjee S, Harvey S, Huber FM, Lin DH, Brown B, Tang AW, Rundlet EJ, Correia AR, Chen S, Regmi SG, Stevens TA, Jette CA, Dasso M, Patke A, Palazzo AF, Kossiakoff AA, Hoelz A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156043 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 SUMO-protein ligase RanBP2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 30 amino acids
Theoretical weight: 3.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49792 (Residues: 805-832; Coverage: 1%)
Gene names: NUP358, RANBP2

Ligands and Environments

2 bound ligands:
Ligand EDO 4 x EDO
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: I422
Unit cell:
a: 99.93Å b: 99.93Å c: 60.16Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.155 0.167
Expression system: Escherichia coli

Quick links

Citations

13 review citations

The Nuclear Pore Complex: Birth, Life, and Death of a Cellular Behemoth.
Dultz et al. (2022)
12 more

1 mention without citation

Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling.
Wang et al. (2023)