Function and Biology

Crystal Structure of Nup358/RanBP2 Ran-binding domain 4 in complex with Ran-GPPNHP

Source organism: Homo sapiens
Biochemical function: pre-miRNA binding
Biological process: intracellular transport
Cellular component: Flemming body

Sequence families

Pfam Protein families (Pfam)
PF00638
Domain description: RanBP1 domain
Occurring in:
  1. E3 SUMO-protein ligase RanBP2
The deposited structure of PDB entry 7mnz contains 6 copies of Pfam domain PF00638 (RanBP1 domain) in E3 SUMO-protein ligase RanBP2. Showing 1 copy in chain B.

PF00071
Domain description: Ras family
Occurring in:
  1. GTP-binding nuclear protein Ran
The deposited structure of PDB entry 7mnz contains 6 copies of Pfam domain PF00071 (Ras family) in GTP-binding nuclear protein Ran. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002041
Domain description: Ran GTPase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR000156
Domain description: Ran binding domain
Occurring in:
  1. E3 SUMO-protein ligase RanBP2
IPR001806
Domain description: Small GTPase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR045255
Domain description: Ran binding protein RanBP1-like
Occurring in:
  1. E3 SUMO-protein ligase RanBP2
IPR011993
Domain description: PH-like domain superfamily
Occurring in:
  1. E3 SUMO-protein ligase RanBP2
IPR005225
Domain description: Small GTP-binding domain
Occurring in:
  1. GTP-binding nuclear protein Ran