EC 3.1.11.5: Exodeoxyribonuclease V
Reaction catalysed:
Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides
Alternative Name(s):
- E. coli exonuclease V
- E.coli exonuclease V
- Escherichia coli exonuclease V
- Exonuclease V
- Gene recBC DNase
- Gene recBC endoenzyme
- Gene recBCD enzymes
- RecBC deoxyribonuclease
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF13538 (UvrD-like helicase C-terminal domain) in RecBCD enzyme subunit RecD. Showing 1 copy in chain C [auth D] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_3_D_Pfam_PF13538_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF13538 (UvrD-like helicase C-terminal domain)</span> in <span class='highlight'>RecBCD enzyme subunit RecD</span>. Showing 1 copy in chain <span class='highlight'>C [auth D]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF13245 (AAA domain) in RecBCD enzyme subunit RecD. Showing 1 copy in chain C [auth D] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_3_D_Pfam_PF13245_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF13245 (AAA domain)</span> in <span class='highlight'>RecBCD enzyme subunit RecD</span>. Showing 1 copy in chain <span class='highlight'>C [auth D]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF21185 (RecBCD enzyme subunit RecD, N-terminal domain) in RecBCD enzyme subunit RecD. Showing 1 copy in chain C [auth D].](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_3_D_Pfam_PF21185_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF21185 (RecBCD enzyme subunit RecD, N-terminal domain)</span> in <span class='highlight'>RecBCD enzyme subunit RecD</span>. Showing 1 copy in chain <span class='highlight'>C [auth D]</span>.")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF17946 (RecC C-terminal domain) in RecBCD enzyme subunit RecC. Showing 1 copy in chain B [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_2_C_Pfam_PF17946_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF17946 (RecC C-terminal domain)</span> in <span class='highlight'>RecBCD enzyme subunit RecC</span>. Showing 1 copy in chain <span class='highlight'>B [auth C]</span>.")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF04257 (Exodeoxyribonuclease V, gamma subunit ) in RecBCD enzyme subunit RecC. Showing 1 copy in chain B [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_2_C_Pfam_PF04257_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF04257 (Exodeoxyribonuclease V, gamma subunit )</span> in <span class='highlight'>RecBCD enzyme subunit RecC</span>. Showing 1 copy in chain <span class='highlight'>B [auth C]</span>.")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF12705 (PD-(D/E)XK nuclease superfamily) in RecBCD enzyme subunit RecB. Showing 1 copy in chain A [auth B] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_1_B_Pfam_PF12705_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF12705 (PD-(D/E)XK nuclease superfamily)</span> in <span class='highlight'>RecBCD enzyme subunit RecB</span>. Showing 1 copy in chain <span class='highlight'>A [auth B]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF13361 (UvrD-like helicase C-terminal domain) in RecBCD enzyme subunit RecB. Showing 1 copy in chain A [auth B].](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_1_B_Pfam_PF13361_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF13361 (UvrD-like helicase C-terminal domain)</span> in <span class='highlight'>RecBCD enzyme subunit RecB</span>. Showing 1 copy in chain <span class='highlight'>A [auth B]</span>.")
![The deposited structure of PDB entry 7mr2 contains 1 copy of Pfam domain PF00580 (UvrD/REP helicase N-terminal domain) in RecBCD enzyme subunit RecB. Showing 1 copy in chain A [auth B].](https://www.ebi.ac.uk/pdbe/static/entry/7mr2_1_B_Pfam_PF00580_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7mr2</span> contains 1 copy of Pfam domain <span class='highlight'>PF00580 (UvrD/REP helicase N-terminal domain)</span> in <span class='highlight'>RecBCD enzyme subunit RecB</span>. Showing 1 copy in chain <span class='highlight'>A [auth B]</span>.")
InterPro annotations
IPR041851
Domain description:
RecBCD enzyme subunit RecD, N-terminal domain superfamily
Occurring in:
Occurring in: