› 7mro

X-ray diffraction
1.87Å resolution

Zebrafish CNTN4 FN1-FN3 domains

Released:
DOI: 10.2210/pdb7mro/pdb
PDB entry 7mro coloured by chain, front view.
PDB entry 7mro coloured by chain, side view.
PDB entry 7mro coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface.
Karuppan SJ, Vogt A, Fischer Z, Ladutska A, Swiastyn J, McGraw HF, Bouyain S
OpenAccess logo J Biol Chem 298 101541 (2022)
PMID: 34958801

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123346 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Contactin 4 Chain: A
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 33.22 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: F1QGN2 (Residues: 600-903; Coverage: 30%)
Gene names: cntn4, zgc:153573
Sequence domains: Fibronectin type III domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 44.7Å b: 56.88Å c: 130.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.174 0.216
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Amyloid precursor protein (APP) and amyloid β (Aβ) interact with cell adhesion molecules: Implications in Alzheimer's disease and normal physiology.
Pfundstein et al. (2022)
1 more

2 mentions without citation

Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface.
Karuppan et al. (2022)
1 more