› 7mx0

X-ray diffraction
2.48Å resolution

The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988558

Released:
DOI: 10.2210/pdb7mx0/pdb
PDB entry 7mx0 coloured by chain, front view.
PDB entry 7mx0 coloured by chain, side view.
PDB entry 7mx0 coloured by chain, top view.
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Entry authors: Cuypers MG, Slavish JP, Rankovic Z, White SW

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111236 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase acidic protein Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 23.15 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C3W5S0 (Residues: 1-50, 73-196; Coverage: 24%)
Gene name: PA

Ligands and Environments

4 bound ligands:
Ligand MN 2 x MN
Ligand WTD 1 x WTD
Ligand QQ4 1 x QQ4
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: I422
Unit cell:
a: 89.631Å b: 89.631Å c: 133.93Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.209 0.257
Expression system: Escherichia coli BL21(DE3)

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