Function and Biology Details
Reaction catalysed:
Acetyl-CoA + an N-terminal-L-methionyl-L-isoleucyl-[protein] = an N-terminal-N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein] + CoA
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-168511 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
N-alpha-acetyltransferase 35, NatC auxiliary subunit
Molecule details ›
Chain: B
Length: 725 amino acids
Theoretical weight: 83.75 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Mak10 subunit, NatC N(alpha)-terminal acetyltransferase
Length: 725 amino acids
Theoretical weight: 83.75 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q5VZE5 (Residues: 1-725; Coverage: 100%)
Sequence domains: Mak10 subunit, NatC N(alpha)-terminal acetyltransferase
N-alpha-acetyltransferase 38, NatC auxiliary subunit
Molecule details ›
Chain: C
Length: 125 amino acids
Theoretical weight: 13.53 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: LSM domain
Length: 125 amino acids
Theoretical weight: 13.53 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q9BRA0 (Residues: 1-125; Coverage: 100%)
Sequence domains: LSM domain
N-alpha-acetyltransferase 30
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 18.08 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Acetyltransferase (GNAT) family
Length: 152 amino acids
Theoretical weight: 18.08 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q147X3 (Residues: 211-362; Coverage: 42%)
Sequence domains: Acetyltransferase (GNAT) family
