7n05

X-ray diffraction
1.7Å resolution

Crystal structure of the F240 antibody fragment bound to the HIV-1 gp41 immunodominant region

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-209091 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fab F240 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 246 amino acids
Theoretical weight: 26.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Fab F240 light chain Chain: L
Molecule details ›
Chain: L
Length: 220 amino acids
Theoretical weight: 24.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Transmembrane protein gp41 Chain: E
Molecule details ›
Chain: E
Length: 16 amino acids
Theoretical weight: 1.62 KDa
Source organism: HIV-1 06TG.HT008
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 596-610; Coverage: 2%)
Gene name: env

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 46.072Å b: 168.748Å c: 78.367Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.172 0.204
Expression systems:
  • Homo sapiens
  • Not provided