7n2r

X-ray diffraction
2.28Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-233106 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
AS4.3 T cell receptor alpha chain Chain: D
Molecule details ›
Chain: D
Length: 204 amino acids
Theoretical weight: 22.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
AS4.3 T cell receptor beta chain Chain: F
Molecule details ›
Chain: F
Length: 242 amino acids
Theoretical weight: 27.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 32.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A3F718 (Residues: 11-288; Coverage: 94%)
Gene name: HLA-B
Sequence domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
U4/U6 small nuclear ribonucleoprotein Prp3 Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 984 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43395 (Residues: 368-376; Coverage: 1%)
Gene names: HPRP3, PRP3, PRPF3

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-1
Spacegroup: P212121
Unit cell:
a: 54.68Å b: 94.423Å c: 178.522Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.248 0.288
Expression systems:
  • Homo sapiens
  • Escherichia coli
  • Not provided