› 7n5f

Electron Microscopy
2.7Å resolution

Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN

Released:
DOI: 10.2210/pdb7n5f/pdb
PDB entry 7n5f coloured by chain, front view.
PDB entry 7n5f coloured by chain, side view.
PDB entry 7n5f coloured by chain, top view.
Source organism: Dionaea muscipula
Primary publication:
Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Jojoa-Cruz S, Saotome K, Tsui CCA, Lee WH, Sansom MSP, Murthy SE, Patapoutian A, Ward AB
OpenAccess logo Nat Commun 13 850 (2022)
PMID: 35165281
Related structures: EMD-24188

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105923 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mechanosensitive ion channel protein Chain: A
Molecule details ›
Chain: A
Length: 762 amino acids
Theoretical weight: 86.81 KDa
Source organism: Dionaea muscipula
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A7U3W892 (Residues: 1-752; Coverage: 100%)
Gene name: FLYC1
Sequence domains: Mechanosensitive ion channel, beta-domain

Ligands and Environments

1 bound ligand:
Ligand PLM 1 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-24188
Expression system: Homo sapiens

Quick links

Citations

3 review citations

How Functional Lipids Affect the Structure and Gating of Mechanosensitive MscS-like Channels.
Flegler et al. (2022)
2 more