Function and Biology

Structure of Acetyl-CoA acetyltransferase from Syntrophomonas wolfei

Source organism: Syntrophomonas wolfei subsp. wolfei str. Goettingen G311
Biochemical function: acyltransferase activity, transferring groups other than amino-acyl groups
Biological process: not assigned
Cellular component: not assigned

EC 2.3.1.9: Acetyl-CoA C-acetyltransferase

Reaction catalysed:
(1a) acetyl-CoA + [acetyl-CoA C-acetyltransferase]-L-cysteine = [acetyl-CoA C-acetyltransferase]-S-acetyl-L-cysteine + CoA
Systematic name:
Acetyl-CoA:acetyl-CoA C-acetyltransferase
Alternative Name(s):
  • 2-methylacetoacetyl-CoA thiolase
  • 3-oxothiolase
  • Acetoacetyl-CoA thiolase
  • Acetyl coenzyme A thiolase
  • Acetyl-CoA acetyltransferase
  • Acetyl-CoA:N-acetyltransferase
  • Beta-acetoacetyl coenzyme A thiolase
  • Thiolase II

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF02803
Domain description: Thiolase, C-terminal domain
Occurring in:
  1. Acetyl-CoA acetyltransferase
The deposited structure of PDB entry 7n7z contains 2 copies of Pfam domain PF02803 (Thiolase, C-terminal domain) in Acetyl-CoA C-acetyltransferase. Showing 1 copy in chain B.

PF00108
Domain description: Thiolase, N-terminal domain
Occurring in:
  1. Acetyl-CoA acetyltransferase
The deposited structure of PDB entry 7n7z contains 2 copies of Pfam domain PF00108 (Thiolase, N-terminal domain) in Acetyl-CoA C-acetyltransferase. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR002155
Domain description: Thiolase
Occurring in:
  1. Acetyl-CoA acetyltransferase
IPR020617
Domain description: Thiolase, C-terminal
Occurring in:
  1. Acetyl-CoA acetyltransferase
IPR020616
Domain description: Thiolase, N-terminal
Occurring in:
  1. Acetyl-CoA acetyltransferase