7n84

Electron Microscopy
11.6Å resolution

Double nuclear outer ring from the isolated yeast NPC

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 136-mer (preferred)
PDBe Complex ID:
PDB-CPX-153009 (preferred)
Entry contents:
9 distinct polypeptide molecules
Macromolecules (9 distinct):
Nucleoporin NUP188 Chain: X
Molecule details ›
Chain: X
Length: 1655 amino acids
Theoretical weight: 188.75 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P52593 (Residues: 1-1655; Coverage: 100%)
Gene names: NUP188, YML103C
Sequence domains:
unknown Chains: Y, Z
Molecule details ›
Chains: Y, Z
Length: 63 amino acids
Theoretical weight: 5.38 KDa
Source organism: Saccharomyces cerevisiae
Nucleoporin NUP120 Chains: a, l
Molecule details ›
Chains: a, l
Length: 1037 amino acids
Theoretical weight: 120.56 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P35729 (Residues: 1-1037; Coverage: 100%)
Gene names: NUP120, RAT2, YKL057C, YKL313, YKL314
Sequence domains: Nucleoporin NUP120, helical domain
Nucleoporin NUP85 Chains: b, m
Molecule details ›
Chains: b, m
Length: 744 amino acids
Theoretical weight: 84.97 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P46673 (Residues: 1-744; Coverage: 100%)
Gene names: J1624, NUP85, RAT9, YJR042W
Sequence domains: Nup85 Nucleoporin
Nucleoporin NUP145C Chains: c, n
Molecule details ›
Chains: c, n
Length: 712 amino acids
Theoretical weight: 81.16 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P49687 (Residues: 606-1317; Coverage: 54%)
Gene names: NUP145, RAT10, YGL092W
Sequence domains: Nuclear protein 96
Protein transport protein SEC13 Chains: d, o
Molecule details ›
Chains: d, o
Length: 297 amino acids
Theoretical weight: 33.08 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q04491 (Residues: 1-297; Coverage: 100%)
Gene names: ANU3, L8167.4, SEC13, YLR208W
Sequence domains: WD domain, G-beta repeat
Nucleoporin SEH1 Chains: e, p
Molecule details ›
Chains: e, p
Length: 349 amino acids
Theoretical weight: 39.17 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P53011 (Residues: 1-349; Coverage: 100%)
Gene names: SEH1, YGL100W
Sequence domains: WD domain, G-beta repeat
Nucleoporin NUP84 Chains: f, q
Molecule details ›
Chains: f, q
Length: 726 amino acids
Theoretical weight: 83.72 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P52891 (Residues: 1-726; Coverage: 100%)
Gene names: NUP84, YDL116W
Sequence domains: Nuclear pore protein 84 / 107
Nucleoporin NUP133 Chains: g, r
Molecule details ›
Chains: g, r
Length: 1157 amino acids
Theoretical weight: 133.45 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P36161 (Residues: 1-1157; Coverage: 100%)
Gene names: NUP133, RAT3, YKR082W, YKR402
Sequence domains: Nup133 N terminal like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 11.6Å
Relevant EMDB volumes: EMD-24231