Assemblies
Multimeric state:
hetero 26-mer
Accessible surface area:
263528.67 Å2
Buried surface area:
101229.63 Å2
Dissociation area:
442.21
Å2
Dissociation energy (ΔGdiss):
-1.59
kcal/mol
Dissociation entropy (TΔSdiss):
9.28
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-220475
Macromolecules
Chain: 5
Length: 235 amino acids
Theoretical weight: 28.03 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Nucleolar protein 12 (25kDa)
InterPro: Nucleolar protein 12
Length: 235 amino acids
Theoretical weight: 28.03 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
Q04031 (Residues: 1-235; Coverage: 100%)
Pfam: Nucleolar protein 12 (25kDa)
InterPro: Nucleolar protein 12
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Q04031
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: 8
Length: 710 amino acids
Theoretical weight: 81.72 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Noc2p family
InterPro: Nucleolar complex protein 2
Length: 710 amino acids
Theoretical weight: 81.72 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P39744 (Residues: 1-710; Coverage: 100%)
Pfam: Noc2p family
InterPro: Nucleolar complex protein 2
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P39744
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: B
Length: 387 amino acids
Theoretical weight: 43.85 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L3
InterPro:
Length: 387 amino acids
Theoretical weight: 43.85 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P14126 (Residues: 1-387; Coverage: 100%)
Pfam: Ribosomal protein L3
InterPro:
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P14126
Chains
Domains
Interaction interfaces
Sequence conservation
Chain: G
Length: 256 amino acids
Theoretical weight: 28.18 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Length: 256 amino acids
Theoretical weight: 28.18 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P17076 (Residues: 1-256; Coverage: 100%)
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
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P17076
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: I
Length: 663 amino acids
Theoretical weight: 75.69 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam:
InterPro:
Length: 663 amino acids
Theoretical weight: 75.69 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
Q07896 (Residues: 1-663; Coverage: 100%)
Pfam:
InterPro:
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Q07896
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: P
Length: 184 amino acids
Theoretical weight: 20.59 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L22p/L17e
InterPro:
Length: 184 amino acids
Theoretical weight: 20.59 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P05740 (Residues: 1-184; Coverage: 100%)
Pfam: Ribosomal protein L22p/L17e
InterPro:
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P05740
Chains
Domains
Secondary structure
Sequence conservation
Chain: R
Length: 189 amino acids
Theoretical weight: 21.76 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L19e
InterPro:
Length: 189 amino acids
Theoretical weight: 21.76 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P0CX82 (Residues: 1-189; Coverage: 100%)
Pfam: Ribosomal protein L19e
InterPro:
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P0CX82
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: U
Length: 121 amino acids
Theoretical weight: 13.71 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal L22e protein family
InterPro:
Length: 121 amino acids
Theoretical weight: 13.71 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P05749 (Residues: 1-121; Coverage: 100%)
Pfam: Ribosomal L22e protein family
InterPro:
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P05749
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: V
Length: 36 amino acids
Theoretical weight: 4.02 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L14p/L23e
Length: 36 amino acids
Theoretical weight: 4.02 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P0CX41 (Residues: 17-74; Coverage: 23%)
Pfam: Ribosomal protein L14p/L23e
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P0CX41
Chains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: X
Length: 142 amino acids
Theoretical weight: 15.79 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam:
InterPro:
Length: 142 amino acids
Theoretical weight: 15.79 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P04456 (Residues: 1-142; Coverage: 100%)
Pfam:
InterPro:
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P04456
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: Z
Length: 136 amino acids
Theoretical weight: 15.57 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal L27e protein family
InterPro:
Length: 136 amino acids
Theoretical weight: 15.57 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P0C2H6 (Residues: 1-136; Coverage: 100%)
Pfam: Ribosomal L27e protein family
InterPro:
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P0C2H6
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: b
Length: 647 amino acids
Theoretical weight: 74.53 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam:
InterPro:
Length: 647 amino acids
Theoretical weight: 74.53 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
Q02892 (Residues: 1-647; Coverage: 100%)
Pfam:
InterPro:
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Q02892
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: c
Length: 105 amino acids
Theoretical weight: 11.43 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Length: 105 amino acids
Theoretical weight: 11.43 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P14120 (Residues: 1-105; Coverage: 100%)
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
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P14120
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: d
Length: 113 amino acids
Theoretical weight: 12.98 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L31e
InterPro:
Length: 113 amino acids
Theoretical weight: 12.98 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P0C2H8 (Residues: 1-113; Coverage: 100%)
Pfam: Ribosomal protein L31e
InterPro:
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P0C2H8
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: g
Length: 121 amino acids
Theoretical weight: 13.67 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L34e
InterPro:
Length: 121 amino acids
Theoretical weight: 13.67 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P87262 (Residues: 1-121; Coverage: 100%)
Pfam: Ribosomal protein L34e
InterPro:

P87262
Chains
Domains
Secondary structure
Ligand binding sites
Interaction interfaces
Sequence conservation
Chain: k
Length: 78 amino acids
Theoretical weight: 8.85 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal L38e protein family
InterPro:
Length: 78 amino acids
Theoretical weight: 8.85 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P49167 (Residues: 1-78; Coverage: 100%)
Pfam: Ribosomal L38e protein family
InterPro:

P49167
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: m
Length: 429 amino acids
Theoretical weight: 48.69 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: WD domain, G-beta repeat
InterPro:
Length: 429 amino acids
Theoretical weight: 48.69 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
Q04660 (Residues: 392-563, 564-807; Coverage: 51%)
Pfam: WD domain, G-beta repeat
InterPro:

Q04660
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: n
Length: 104 amino acids
Theoretical weight: 12.45 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Pescadillo N-terminus
InterPro: Pescadillo
Length: 104 amino acids
Theoretical weight: 12.45 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P53261 (Residues: 1-110; Coverage: 17%)
Pfam: Pescadillo N-terminus
InterPro: Pescadillo

P53261
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: p
Length: 460 amino acids
Theoretical weight: 51.43 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam:
InterPro:
Length: 460 amino acids
Theoretical weight: 51.43 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
Q12024 (Residues: 1-460; Coverage: 100%)
Pfam:
InterPro:

Q12024
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Chain: t
Length: 322 amino acids
Theoretical weight: 36.62 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L30p/L7e
InterPro:
Length: 322 amino acids
Theoretical weight: 36.62 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P40693 (Residues: 1-322; Coverage: 100%)
Pfam: Ribosomal protein L30p/L7e
InterPro:

P40693
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: u
Length: 199 amino acids
Theoretical weight: 24.03 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L24e
InterPro:
Length: 199 amino acids
Theoretical weight: 24.03 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
Q07915 (Residues: 1-199; Coverage: 100%)
Pfam: Ribosomal protein L24e
InterPro:

Q07915
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: w
Length: 841 amino acids
Theoretical weight: 96.66 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam:
InterPro:
Length: 841 amino acids
Theoretical weight: 96.66 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P25582 (Residues: 1-841; Coverage: 100%)
Pfam:
InterPro:
- AdoMet-dependent rRNA methyltransferase SPB1-like
- Ribosomal RNA large subunit methyltransferase E
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- Ribosomal RNA methyltransferase, FtsJ domain
- Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381
- Ribosomal RNA methyltransferase, SPB1-like, C-terminal

P25582
Chains
Domains
Secondary structure
Flexibility predictions
Interaction interfaces
Sequence conservation
Chain: j
Length: 88 amino acids
Theoretical weight: 9.88 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam: Ribosomal protein L37e
InterPro:
Length: 88 amino acids
Theoretical weight: 9.88 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P49166 (Residues: 1-88; Coverage: 100%)
Pfam: Ribosomal protein L37e
InterPro:

P49166
Chains
Domains
Secondary structure
Sequence conservation
Chain: x
Length: 606 amino acids
Theoretical weight: 69.49 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
Pfam:
InterPro:
Length: 606 amino acids
Theoretical weight: 69.49 KDa
Source organism: Saccharomyces cerevisiae BY4741
UniProt:
- Canonical:
P25808 (Residues: 1-606; Coverage: 100%)
Pfam:
InterPro:
- P-loop containing nucleoside triphosphate hydrolase
- RNA helicase, DEAD-box type, Q motif
- Helicase superfamily 1/2, ATP-binding domain
- DEAD/DEAH box helicase domain
- ATP-dependent RNA helicase DEAD-box, conserved site
- Helicase, C-terminal domain-like
- ATP-dependent rRNA helicase SPB4-like, C-terminal extension

P25808
Chains
Domains
Secondary structure
Interaction interfaces
Sequence conservation
Name:
25S ribosomal RNA
Representative chains: 1
Length: 697 nucleotides
Theoretical weight: 225.36 KDa
Rfam: Eukaryotic large subunit ribosomal RNA
Representative chains: 1
Length: 697 nucleotides
Theoretical weight: 225.36 KDa
Rfam: Eukaryotic large subunit ribosomal RNA
Chain A (auth 1)
Rfam
Interaction interfaces
Name:
5.8S ribosomal RNA
Representative chains: 2
Length: 72 nucleotides
Theoretical weight: 23.07 KDa
Representative chains: 2
Length: 72 nucleotides
Theoretical weight: 23.07 KDa
Chain B (auth 2)
Interaction interfaces