7ndx

X-ray diffraction
2.54Å resolution

Crystal structure of the human HSP40 DNAJB1-CTDs in complex with a peptide of NudC

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-150554 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DnaJ homolog subfamily B member 1 Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 20.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25685 (Residues: 157-340; Coverage: 54%)
Gene names: DNAJ1, DNAJB1, HDJ1, HSPF1
Sequence domains: DnaJ C terminal domain
Nuclear migration protein nudC Chain: B
Molecule details ›
Chain: B
Length: 42 amino acids
Theoretical weight: 4.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y266 (Residues: 100-141; Coverage: 13%)
Gene name: NUDC
Sequence domains: Nuclear distribution C domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: I212121
Unit cell:
a: 41.3Å b: 128.264Å c: 135.213Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.233 0.268
Expression system: Escherichia coli