7nfy

Electron Microscopy
3.9Å resolution

P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS

Released:
Source organism: Homo sapiens
Related structures: EMD-12306

Function and Biology Details

Reaction catalysed:
Hydrolysis of proteins in presence of ATP.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-153225 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Lon protease homolog, mitochondrial Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 853 amino acids
Theoretical weight: 96.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
substrate protein Chain: G
Molecule details ›
Chain: G
Length: 55 amino acids
Theoretical weight: 4.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-12306
Expression system: Escherichia coli K-12