7ngd

X-ray diffraction
1.47Å resolution

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

Released:
Model geometry
Fit model/data
Source organism: Mycobacterium tuberculosis
Entry authors: Tomlinson CWE, Tatum NJ, Pohl E

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-161781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator EthR Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 23.78 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WMC1 (Residues: 1-216; Coverage: 100%)
Gene names: Rv3855, etaR, ethR
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P41212
Unit cell:
a: 121.445Å b: 121.445Å c: 33.717Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.193 0.211
Expression system: Escherichia coli BL21(DE3)