› 7nie

Electron Microscopy
35Å resolution

putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria

Released:
DOI: 10.2210/pdb7nie/pdb
PDB entry 7nie coloured by chain, front view.
PDB entry 7nie coloured by chain, side view.
PDB entry 7nie coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm.
Leung MR, Zenezini Chiozzi R, Roelofs MC, Hevler JF, Ravi RT, Maitan P, Zhang M, Henning H, Bromfield EG, Howes SC, Gadella BM, Heck AJR, Zeev-Ben-Mordehai T
OpenAccess logo Proc Natl Acad Sci U S A 118 (2021)
PMID: 34737233
Related structures: EMD-12357

Function and Biology Details

Reaction catalysed: 
ATP + glycerol = ADP + sn-glycerol 3-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104112 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
glycerol kinase Chains: A, B, O, P
Molecule details ›
Chains: A, B, O, P
Length: 487 amino acids
Theoretical weight: 53.58 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A287BD08 (Residues: 1-487; Coverage: 93%)
Sequence domains:
Voltage-dependent anion-selective channel protein 2 Chains: C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: C, D, E, F, G, H, I, J, K, L, M, N
Length: 294 amino acids
Theoretical weight: 31.64 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q9MZ15 (Residues: 1-294; Coverage: 100%)
Gene name: VDAC2
Sequence domains: Eukaryotic porin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 35Å
Relevant EMDB volumes: EMD-12357

Quick links

Citations

4 review citations

A Frame-by-Frame Glance at Membrane Fusion Mechanisms: From Viral Infections to Fertilization.
Azimi et al. (2023)
3 more

1 mention without citation

Six Functions of Respiration: Isn't It Time to Take Control over ROS Production in Mitochondria, and Aging Along with It?
Skulachev et al. (2023)