Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tridecamer (preferred)
PDBe Complex ID:
PDB-CPX-121705 (preferred)
Entry contents:
11 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (13 distinct):
General transcription and DNA repair factor IIH helicase subunit XPD
Molecule details ›
Chain: 0
Length: 760 amino acids
Theoretical weight: 87.02 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 760 amino acids
Theoretical weight: 87.02 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P18074 (Residues: 1-760; Coverage: 100%)
Sequence domains:
General transcription factor IIH subunit 1
Molecule details ›
Chain: 1
Length: 548 amino acids
Theoretical weight: 62.12 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 548 amino acids
Theoretical weight: 62.12 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P32780 (Residues: 1-548; Coverage: 100%)
Sequence domains:
General transcription factor IIH subunit 4
Molecule details ›
Chain: 2
Length: 462 amino acids
Theoretical weight: 52.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 462 amino acids
Theoretical weight: 52.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q92759 (Residues: 1-462; Coverage: 100%)
Sequence domains:
CDK-activating kinase assembly factor MAT1
Molecule details ›
General transcription factor IIH subunit 3
Molecule details ›
Chain: 4
Length: 308 amino acids
Theoretical weight: 34.42 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Transcription factor Tfb4
Length: 308 amino acids
Theoretical weight: 34.42 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q13889 (Residues: 1-308; Coverage: 100%)
Sequence domains: Transcription factor Tfb4
General transcription factor IIH subunit 5
Molecule details ›
Chain: 5
Length: 71 amino acids
Theoretical weight: 8.06 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Transcription factor TFIIH complex subunit Tfb5
Length: 71 amino acids
Theoretical weight: 8.06 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q6ZYL4 (Residues: 1-71; Coverage: 100%)
Sequence domains: Transcription factor TFIIH complex subunit Tfb5
General transcription factor IIH subunit 2
Molecule details ›
Chain: 6
Length: 395 amino acids
Theoretical weight: 44.48 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 395 amino acids
Theoretical weight: 44.48 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q13888 (Residues: 1-395; Coverage: 100%)
Sequence domains:
General transcription and DNA repair factor IIH helicase/translocase subunit XPB
Molecule details ›
Chain: 7
Length: 782 amino acids
Theoretical weight: 89.4 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 782 amino acids
Theoretical weight: 89.4 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P19447 (Residues: 1-782; Coverage: 100%)
Sequence domains:
General transcription factor IIE subunit 1
Molecule details ›
Chain: W
Length: 439 amino acids
Theoretical weight: 49.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 439 amino acids
Theoretical weight: 49.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P29083 (Residues: 1-439; Coverage: 100%)
Sequence domains:
