Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 32-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-236748 (preferred)
Entry contents:
30 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (32 distinct):
General transcription and DNA repair factor IIH helicase subunit XPD
Chain: 0
Molecule details ›
Chain: 0
Length: 760 amino acids
Theoretical weight: 87.02 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 760 amino acids
Theoretical weight: 87.02 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIH subunit 1
Chain: 1
Molecule details ›
Chain: 1
Length: 548 amino acids
Theoretical weight: 62.12 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 548 amino acids
Theoretical weight: 62.12 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIH subunit 4
Chain: 2
Molecule details ›
Chain: 2
Length: 462 amino acids
Theoretical weight: 52.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 462 amino acids
Theoretical weight: 52.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
CDK-activating kinase assembly factor MAT1
Chain: 3
Molecule details ›
Chain: 3
Length: 309 amino acids
Theoretical weight: 35.87 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 309 amino acids
Theoretical weight: 35.87 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIH subunit 3
Chain: 4
Molecule details ›
Chain: 4
Length: 308 amino acids
Theoretical weight: 34.42 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 308 amino acids
Theoretical weight: 34.42 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIH subunit 5
Chain: 5
Molecule details ›
Chain: 5
Length: 71 amino acids
Theoretical weight: 8.06 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 71 amino acids
Theoretical weight: 8.06 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIH subunit 2
Chain: 6
Molecule details ›
Chain: 6
Length: 395 amino acids
Theoretical weight: 44.48 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 395 amino acids
Theoretical weight: 44.48 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription and DNA repair factor IIH helicase/translocase subunit XPB
Chain: 7
Molecule details ›
Chain: 7
Length: 782 amino acids
Theoretical weight: 89.4 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 782 amino acids
Theoretical weight: 89.4 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
DNA-directed RNA polymerase subunit
Chain: A
DNA-directed RNA polymerase subunit beta
Chain: B
DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
Chain: C
RNA polymerase Rpb4/RPC9 core domain-containing protein
Chain: D
DNA-directed RNA polymerase II subunit E
Chain: E
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Chain: F
DNA-directed RNA polymerase II subunit RPB7
Chain: G
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Chain: H
DNA-directed RNA polymerase II subunit RPB9
Chain: I
DNA-directed RNA polymerases I, II, and III subunit RPABC5
Chain: J
DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
Chain: K
RNA polymerase II, I and III subunit K
Chain: L
Transcription initiation factor IIB
Chain: M
Molecule details ›
Chain: M
Length: 316 amino acids
Theoretical weight: 34.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 316 amino acids
Theoretical weight: 34.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
TATA-box-binding protein
Chain: O
Molecule details ›
Chain: O
Length: 339 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 339 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIF subunit 1
Chain: Q
Molecule details ›
Chain: Q
Length: 517 amino acids
Theoretical weight: 58.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 517 amino acids
Theoretical weight: 58.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
General transcription factor IIF subunit 2
Chain: R
Molecule details ›
Chain: R
Length: 249 amino acids
Theoretical weight: 28.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 249 amino acids
Theoretical weight: 28.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Transcription initiation factor IIA subunit 1
Chain: U
Molecule details ›
Chain: U
Length: 376 amino acids
Theoretical weight: 41.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 376 amino acids
Theoretical weight: 41.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Transcription initiation factor IIA subunit 2
Chain: V
Molecule details ›
Chain: V
Length: 109 amino acids
Theoretical weight: 12.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 109 amino acids
Theoretical weight: 12.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIE subunit 1
Chain: W
Molecule details ›
Chain: W
Length: 439 amino acids
Theoretical weight: 49.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 439 amino acids
Theoretical weight: 49.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Transcription initiation factor IIE subunit beta
Chain: X
Molecule details ›
Chain: X
Length: 291 amino acids
Theoretical weight: 33.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 291 amino acids
Theoretical weight: 33.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Unassigned peptide, likely TFIIE-beta
Chain: Y
Molecule details ›
Chain: Y
Length: 19 amino acids
Theoretical weight: 1.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 19 amino acids
Theoretical weight: 1.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Unassigned peptide, likely XPB
Chain: Z
Molecule details ›
Chain: Z
Length: 8 amino acids
Theoretical weight: 699 Da
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 8 amino acids
Theoretical weight: 699 Da
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Non-template DNA
Chain: N
Molecule details ›
Chain: N
Length: 106 nucleotides
Theoretical weight: 32.91 KDa
Source organism: Human mastadenovirus C
Expression system: Not provided
Length: 106 nucleotides
Theoretical weight: 32.91 KDa
Source organism: Human mastadenovirus C
Expression system: Not provided
Template DNA
Chain: T
Molecule details ›
Chain: T
Length: 106 nucleotides
Theoretical weight: 32.51 KDa
Source organism: Human mastadenovirus C
Expression system: Not provided
Length: 106 nucleotides
Theoretical weight: 32.51 KDa
Source organism: Human mastadenovirus C
Expression system: Not provided