Function and Biology

14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-125

Source organism: Homo sapiens
Biochemical function: protein sequestering activity
Biological process: negative regulation of stem cell proliferation
Cellular component: extracellular exosome

Sequence family

Pfam Protein family (Pfam)
PF00244
Domain description: 14-3-3 protein
Occurring in:
  1. 14-3-3 protein sigma
The deposited structure of PDB entry 7nz6 contains 1 copy of Pfam domain PF00244 (14-3-3 protein) in 14-3-3 protein sigma. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000308
Domain description: 14-3-3 protein
Occurring in:
  1. 14-3-3 protein sigma
IPR023410
Domain description: 14-3-3 domain
Occurring in:
  1. 14-3-3 protein sigma
IPR036815
Domain description: 14-3-3 domain superfamily
Occurring in:
  1. 14-3-3 protein sigma
IPR023409
Domain description: 14-3-3 protein, conserved site
Occurring in:
  1. 14-3-3 protein sigma