› 7o88

X-ray diffraction
1.2Å resolution

Cystal structure of Zymogen Granule Protein 16 (ZG16)

Released:
DOI: 10.2210/pdb7o88/pdb
PDB entry 7o88 coloured by chain, front view.
PDB entry 7o88 coloured by chain, side view.
PDB entry 7o88 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Conformational switches and redox properties of the colon cancer-associated human lectin ZG16.
Javitt G, Kinzel A, Reznik N, Fass D
OpenAccess logo FEBS J 288 6465-6475 (2021)
PMID: 34077620

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-521177 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zymogen granule membrane protein 16 Chains: A, B
Molecule details ›
Chains: A, B
Length: 148 amino acids
Theoretical weight: 16.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60844 (Residues: 21-167; Coverage: 97%)
Gene name: ZG16
Sequence domains: Jacalin-like lectin domain

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 44.978Å b: 45.418Å c: 146.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.173 0.191
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Flagella at the Host-Microbe Interface: Key Functions Intersect With Redundant Responses.
Akahoshi et al. (2022)
1 other article

1 mention without citation

Conformational switches and redox properties of the colon cancer-associated human lectin ZG16.
Javitt et al. (2021)