Function and Biology

Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)

Source organism: Rattus norvegicus
Biochemical function: signaling receptor activity
Biological process: monoatomic ion transport
Cellular component: membrane

Sequence families

Pfam Protein families (Pfam)
PF03311
Domain description: Cornichon protein
Occurring in:
  1. Protein cornichon homolog 2

PF00060
Domain description: Ligand-gated ion channel
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2

PF10613
Domain description: Ligated ion channel L-glutamate- and glycine-binding site
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2

PF01094
Domain description: Receptor family ligand binding region
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2

PF00822
Domain description: PMP-22/EMP/MP20/Claudin family
Occurring in:
  1. Voltage-dependent calcium channel gamma-8 subunit

InterPro InterPro annotations
IPR001508
Domain description: Ionotropic glutamate receptor, metazoa
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2
IPR019594
Domain description: Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2
IPR001320
Domain description: Ionotropic glutamate receptor, C-terminal
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2
IPR008368
Domain description: Voltage-dependent calcium channel, gamma subunit
Occurring in:
  1. Voltage-dependent calcium channel gamma-8 subunit
IPR003377
Domain description: Cornichon
Occurring in:
  1. Protein cornichon homolog 2
IPR008372
Domain description: Voltage-dependent calcium channel, gamma-8 subunit
Occurring in:
  1. Voltage-dependent calcium channel gamma-8 subunit
IPR015683
Domain description: Ionotropic glutamate receptor
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2
IPR001828
Domain description: Receptor, ligand binding region
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2
IPR028082
Domain description: Periplasmic binding protein-like I
Occurring in:
  1. Glutamate receptor 1
  2. Glutamate receptor 2
IPR004031
Domain description: PMP-22/EMP/MP20/Claudin
Occurring in:
  1. Voltage-dependent calcium channel gamma-8 subunit
IPR033466
Domain description: Cornichon, conserved site
Occurring in:
  1. Protein cornichon homolog 2