7oeb

Electron Microscopy
3.04Å resolution

Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO]

Released:

Function and Biology Details

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-497555 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
RNA-directed RNA polymerase L Chain: L
Molecule details ›
Chain: L
Length: 2217 amino acids
Theoretical weight: 253.66 KDa
Source organism: Mammarenavirus lassaense
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A3S8NV63 (Residues: 1-2217; Coverage: 100%)
Gene name: L
Sequence domains:
3' vRNA Chain: E
Molecule details ›
Chain: E
Length: 16 nucleotides
Theoretical weight: 5.11 KDa
Source organism: Mammarenavirus lassaense
Expression system: Trichoplusia ni

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.04Å
Relevant EMDB volumes: EMD-12863
Expression system: Trichoplusia ni