7oic

Electron Microscopy
3.1Å resolution

Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4

Released:
Source organism: Homo sapiens
Related structures: EMD-12925

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 57-mer (preferred)
PDBe Complex ID:
PDB-CPX-251707 (preferred)
Entry contents:
55 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (57 distinct):
Large ribosomal subunit protein uL2m Chain: D
Molecule details ›
Chain: D
Length: 305 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q5T653 (Residues: 1-305; Coverage: 100%)
Gene names: CGI-22, MRPL2
Sequence domains:
Large ribosomal subunit protein uL3m Chain: E
Molecule details ›
Chain: E
Length: 348 amino acids
Theoretical weight: 38.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P09001 (Residues: 1-348; Coverage: 100%)
Gene names: MRL3, MRPL3, RPML3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4m Chain: F
Large ribosomal subunit protein bL9m Chain: H
Large ribosomal subunit protein uL10m Chain: I
Large ribosomal subunit protein uL11m Chain: J
Large ribosomal subunit protein uL13m Chain: K
Large ribosomal subunit protein uL14m Chain: L
Large ribosomal subunit protein uL15m Chain: M
Large ribosomal subunit protein uL16m Chain: N
Large ribosomal subunit protein bL17m Chain: O
Large ribosomal subunit protein uL18m Chain: P
Large ribosomal subunit protein bL19m Chain: Q
Large ribosomal subunit protein bL20m Chain: R
Large ribosomal subunit protein bL21m Chain: S
Large ribosomal subunit protein uL22m Chain: T
Large ribosomal subunit protein uL23m Chain: U
Large ribosomal subunit protein uL24m Chain: V
Large ribosomal subunit protein bL27m Chain: W
Large ribosomal subunit protein bL28m Chain: X
Large ribosomal subunit protein uL29m Chain: Y
Large ribosomal subunit protein uL30m Chain: Z
Large ribosomal subunit protein bL32m Chain: 0
Large ribosomal subunit protein bL33m Chain: 1
Large ribosomal subunit protein bL34m Chain: 2
Large ribosomal subunit protein bL35m Chain: 3
Large ribosomal subunit protein bL36m Chain: 4
Large ribosomal subunit protein mL37 Chain: 5
Large ribosomal subunit protein mL38 Chain: 6
Large ribosomal subunit protein mL39 Chain: 7
Large ribosomal subunit protein mL40 Chain: 8
Large ribosomal subunit protein mL41 Chain: 9
Large ribosomal subunit protein mL42 Chain: a
Large ribosomal subunit protein mL43 Chain: b
Large ribosomal subunit protein mL44 Chain: c
Large ribosomal subunit protein mL45 Chain: d
Large ribosomal subunit protein mL46 Chain: e
Large ribosomal subunit protein mL48 Chain: f
Large ribosomal subunit protein mL49 Chain: g
Large ribosomal subunit protein mL50 Chain: h
Large ribosomal subunit protein mL51 Chain: i
Large ribosomal subunit protein mL52 Chain: j
Large ribosomal subunit protein mL53 Chain: k
Large ribosomal subunit protein mL54 Chain: l
Large ribosomal subunit protein mL55 Chain: m
Large ribosomal subunit protein mL63 Chain: o
Large ribosomal subunit protein mL62 Chain: p
Large ribosomal subunit protein mL64 Chain: q
Large ribosomal subunit protein mL66 Chain: r
Large ribosomal subunit protein mL65 Chain: s
Mitochondrial assembly of ribosomal large subunit protein 1 Chain: u
Mitochondrial ribosome and complex I assembly factor AltMIEF1 Chain: v
Acyl carrier protein, mitochondrial Chain: w
5-cytosine rRNA methyltransferase NSUN4 Chain: x
Transcription termination factor 4, mitochondrial Chain: y
16S ribosomal RNA Chain: A
mitochondrial Val tRNA Chain: B

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-12925