7ojn

Electron Microscopy
2.92Å resolution

Lassa virus L protein in an elongation conformation [ELONGATION]

Released:

Function and Biology Details

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-104987 (preferred)
Entry contents:
1 distinct polypeptide molecule
3 distinct RNA molecules
Macromolecules (4 distinct):
RNA-directed RNA polymerase L Chain: L
Molecule details ›
Chain: L
Length: 2217 amino acids
Theoretical weight: 253.66 KDa
Source organism: Mammarenavirus lassaense
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A3S8NV63 (Residues: 1-2217; Coverage: 100%)
Gene name: L
Sequence domains:
5' RNA Chain: D
Molecule details ›
Chain: D
Length: 20 nucleotides
Theoretical weight: 6.45 KDa
Source organism: Mammarenavirus lassaense
Expression system: Not provided
3' RNA Chains: E, R
Molecule details ›
Chains: E, R
Length: 19 nucleotides
Theoretical weight: 6.07 KDa
Source organism: Mammarenavirus lassaense
Expression system: Not provided
product RNA Chain: M
Molecule details ›
Chain: M
Length: 9 nucleotides
Theoretical weight: 2.85 KDa
Source organism: Mammarenavirus lassaense

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.92Å
Relevant EMDB volumes: EMD-12956
Expression systems:
  • Trichoplusia ni
  • Not provided