Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA polymerase II, heptapeptide repeat, eukaryotic
- WD40 repeat
- WD40/YVTN repeat-like-containing domain superfamily
- Zinc finger, TFIIS-type
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- Nucleic acid-binding, OB-fold
- RNA polymerase, RBP11-like subunit
- Helicase, C-terminal domain-like
76 more domains
Structure analysis Details
Assembly composition:
hetero icosamer (preferred)
PDBe Complex ID:
PDB-CPX-236758 (preferred)
Entry contents:
17 distinct polypeptide molecules
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (20 distinct):
DNA-directed RNA polymerase II subunit RPB1
Molecule details ›
Chain: A
Length: 1970 amino acids
Theoretical weight: 217.45 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains:
Length: 1970 amino acids
Theoretical weight: 217.45 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
P11414 (Residues: 1-1970; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit beta
Molecule details ›
Chain: B
Length: 1174 amino acids
Theoretical weight: 134.04 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains:
Length: 1174 amino acids
Theoretical weight: 134.04 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: I3LGP4 (Residues: 127-1300; Coverage: 90%)
Sequence domains:
DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
RNA polymerase Rpb4/RPC9 core domain-containing protein
DNA-directed RNA polymerase II subunit E
DNA-directed RNA polymerases I, II, and III subunit RPABC2
DNA-directed RNA polymerases I, II, and III subunit RPABC3
DNA-directed RNA polymerase II subunit RPB9
DNA-directed RNA polymerases I, II, and III subunit RPABC5
DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
RNA polymerase II, I and III subunit K
DNA excision repair protein ERCC-8
DNA excision repair protein ERCC-6
UV-stimulated scaffold protein A
DNA damage-binding protein 1
