› 7op1

Electron Microscopy
3.7Å resolution

Cryo-EM structure of P5B-ATPase E2PiAlF/SPM

Released:
DOI: 10.2210/pdb7op1/pdb
PDB entry 7op1 coloured by chain, front view.
PDB entry 7op1 coloured by chain, side view.
PDB entry 7op1 coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Structure and transport mechanism of P5B-ATPases.
Li P, Wang K, Salustros N, Grønberg C, Gourdon P
Nat Commun 12 3973 (2021)
PMID: 34172751
Related structures: EMD-13011

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124036 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation-transporting ATPase Chain: A
Molecule details ›
Chain: A
Length: 1393 amino acids
Theoretical weight: 156.01 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: G0S7G9 (Residues: 1-1388; Coverage: 100%)
Gene name: CTHT_0028100
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand ALF 1 x ALF
Ligand SPM 1 x SPM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-13011
Expression system: Saccharomyces cerevisiae

Quick links

Citations

2 review citations

Metabolism of Polyamines and Kidney Disease: A Promising Therapeutic Target.
Luo et al. (2023)
1 more

1 mention without citation

In silico identification of Theileria parva surface proteins.
Gurav et al. (2022)