› 7oqg

X-ray diffraction
1.5Å resolution

Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ136

Released:
DOI: 10.2210/pdb7oqg/pdb
PDB entry 7oqg coloured by chain, front view.
PDB entry 7oqg coloured by chain, side view.
PDB entry 7oqg coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Centorrino F, Ottmann C

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152160 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein sigma Chain: A
Molecule details ›
Chain: A
Length: 253 amino acids
Theoretical weight: 28.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31947 (Residues: 1-248; Coverage: 100%)
Gene names: HME1, SFN
Sequence domains: 14-3-3 protein
Angiomotin Chain: P
Molecule details ›
Chain: P
Length: 13 amino acids
Theoretical weight: 1.63 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q4VCS5 (Residues: 169-181; Coverage: 1%)
Gene names: AMOT, KIAA1071

Ligands and Environments

3 bound ligands:
Ligand 0AW 3 x 0AW
Ligand BME 1 x BME
Ligand MG 1 x MG
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: C2221
Unit cell:
a: 82.81Å b: 111.321Å c: 61.769Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.16 0.178
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links