› 7oqw

X-ray diffraction
1.9Å resolution

Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ178

Released:
DOI: 10.2210/pdb7oqw/pdb
PDB entry 7oqw coloured by chain, front view.
PDB entry 7oqw coloured by chain, side view.
PDB entry 7oqw coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Centorrino F, Ottmann C

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152160 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein sigma Chain: A
Molecule details ›
Chain: A
Length: 253 amino acids
Theoretical weight: 28.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31947 (Residues: 1-248; Coverage: 100%)
Gene names: HME1, SFN
Sequence domains: 14-3-3 protein
Angiomotin Chain: P
Molecule details ›
Chain: P
Length: 13 amino acids
Theoretical weight: 1.63 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q4VCS5 (Residues: 169-181; Coverage: 1%)
Gene names: AMOT, KIAA1071

Ligands and Environments

2 bound ligands:
Ligand 0B7 2 x 0B7
Ligand MG 2 x MG
2 modified residues:
Ligand CSO 1 x CSO
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-003
Spacegroup: C2221
Unit cell:
a: 82.678Å b: 111.644Å c: 61.737Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.221
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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