› 7osc

Solution NMR

Solution structure of antimicrobial peptide cathelicidin-1 PcDode from sperm whale Physeter catodon

Released:
DOI: 10.2210/pdb7osc/pdb
PDB entry 7osc coloured by chain, ensemble of 20 models, front view.
PDB entry 7osc coloured by chain, ensemble of 20 models, side view.
PDB entry 7osc coloured by chain, ensemble of 20 models, top view.
Source organism: Physeter catodon
Primary publication:
Dodecapeptide Cathelicidins of Cetartiodactyla: Structure, Mechanism of Antimicrobial Action, and Synergistic Interaction With Other Cathelicidins
Bolosov IA, Panteleev PV, Sychev SV, Sukhanov SV, Mironov PA, Myshkin MY, Shenkarev ZO, Ovchinnikova TV
Front Microbiol 12 2249- (2021)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-279010 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cathelicidin-1-like Chain: A
Molecule details ›
Chain: A
Length: 24 amino acids
Theoretical weight: 2.79 KDa
Source organism: Physeter catodon
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A2Y9FJE4 (Residues: 279-302; Coverage: 8%)
Gene name: LOC102973809

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 69%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

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